Weihong Chen Selected Research

Silicon Dioxide (Silica)

5/2024	Incidence, mortality, and disability-adjusted life years due to silicosis worldwide, 1990-2019: evidence from the global burden of disease study 2019.
1/2024	ALKBH5 mediates silica particles-induced pulmonary inflammation through increased m6A modification of Slamf7 and autophagy dysfunction.
4/2023	Neutralization of interleukin-11 attenuates silica particles-induced pulmonary inflammation and fibrosis in vivo.
1/2023	The prevalences and levels of occupational exposure to dusts and/or fibres (silica, asbestos and coal): A systematic review and meta-analysis from the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury.
12/2022	Insights into the mechanism underlying crystalline silica-induced pulmonary fibrosis via transcriptome-wide m6A methylation profile.
8/2022	Inhibition of Gas6 promotes crystalline silica-induced inflammatory response of macrophages via blocking autophagy flux.
1/2022	Current global perspectives on silicosis-Convergence of old and newly emergent hazards.
10/2021	Triiodothyronine ameliorates silica-induced pulmonary inflammation and fibrosis in mice.
5/2021	Extracellular signal-regulated kinase signaling pathway and silicosis.
2/2021	Gas6 or Mer deficiency ameliorates silica-induced autophagosomes accumulation in mice lung.

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Weihong Chen Research Topics

Disease

31	Inflammation (Inflammations) 05/2024 - 11/2013
26	Neoplasms (Cancer) 01/2024 - 12/2004
24	Silicosis 05/2024 - 02/2006
16	Type 2 Diabetes Mellitus (MODY) 08/2023 - 01/2016
14	Lung Neoplasms (Lung Cancer) 01/2020 - 12/2004
13	Cardiovascular Diseases (Cardiovascular Disease) 03/2024 - 01/2012
12	Fibrosis (Cirrhosis) 10/2023 - 12/2004
11	Insulin Resistance 08/2023 - 12/2022
9	Pneumoconiosis 01/2023 - 12/2004
8	Lung Diseases (Lung Disease) 05/2024 - 05/2012
8	Pneumonia (Pneumonitis) 05/2024 - 11/2013
8	Hypertension (High Blood Pressure) 02/2024 - 01/2013
6	Respiratory Tract Diseases (Respiratory Tract Disease) 05/2024 - 02/2006
6	Dyslipidemias (Dyslipidemia) 03/2024 - 01/2019
6	Asthma (Bronchial Asthma) 02/2021 - 01/2016
5	Pulmonary Fibrosis (Fibrosing Alveolitis) 12/2022 - 09/2019
4	Genetic Risk Score 03/2024 - 08/2013
4	Metabolic Syndrome (Dysmetabolic Syndrome X) 02/2024 - 08/2013
4	Obesity 07/2023 - 10/2017
4	Coronary Disease (Coronary Heart Disease) 04/2023 - 03/2017
4	Hearing Loss (Hearing Impairment) 04/2023 - 01/2015
4	Abdominal Obesity 01/2019 - 05/2017
4	Anthracosis 08/2016 - 08/2010
3	Interstitial Lung Diseases (Interstitial Lung Disease) 05/2024 - 10/2021
3	Genetic Predisposition to Disease (Genetic Predisposition) 03/2024 - 01/2022
3	Non-alcoholic Fatty Liver Disease 10/2023 - 01/2016
3	Gallbladder Neoplasms (Gallbladder Cancer) 09/2023 - 01/2020
3	Metabolic Diseases (Metabolic Disease) 04/2023 - 02/2019
3	Hyperglycemia 01/2023 - 01/2022
3	Occupational Diseases (Occupational Disease) 12/2022 - 11/2008
3	Chronic Obstructive Pulmonary Disease (COPD) 05/2021 - 05/2015
3	Tuberculosis (Tuberculoses) 01/2021 - 01/2012
3	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 01/2013
3	Carcinogenesis 07/2019 - 09/2006
3	Pain (Aches) 10/2018 - 02/2015
3	Myocardial Ischemia (Ischemic Heart Diseases) 08/2017 - 01/2012
3	Infections 12/2015 - 02/2015
2	Atrial Fibrillation 06/2023 - 01/2021
2	Adenocarcinoma 01/2023 - 08/2012
2	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2023 - 04/2021
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2023 - 03/2018
2	Prediabetic State (Prediabetes) 01/2023 - 01/2023

Drug/Important Bio-Agent (IBA)

38	Silicon Dioxide (Silica)FDA LinkGeneric 05/2024 - 02/2006
21	Biomarkers (Surrogate Marker)IBA 05/2024 - 07/2006
17	Glucose (Dextrose)FDA LinkGeneric 11/2023 - 01/2015
16	Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)IBA 01/2024 - 09/2006
13	Proteins (Proteins, Gene)FDA Link 10/2023 - 05/2007
12	ORALIT (ORS)IBA 01/2023 - 01/2013
10	C-Reactive ProteinIBA 07/2023 - 12/2019
9	LipidsIBA 03/2024 - 01/2017
8	Coal (Coals)IBA 03/2024 - 08/2010
6	CopperIBA 01/2021 - 02/2007
6	TinIBA 01/2020 - 12/2004
5	Triglycerides (Triacylglycerol)IBA 03/2024 - 01/2019
5	BilirubinIBA 10/2023 - 01/2016
5	Insulin (Novolin)FDA Link 08/2023 - 12/2022
5	ZincIBA 01/2023 - 01/2016
5	hydroxide ionIBA 01/2019 - 01/2016
4	MicroRNAs (MicroRNA)IBA 02/2024 - 09/2019
4	CytokinesIBA 01/2024 - 05/2014
4	Acrolein (Aqualin)IBA 10/2023 - 01/2022
4	EnzymesIBA 01/2023 - 06/2007
4	CollagenIBA 10/2021 - 11/2013
4	IronIBA 01/2020 - 02/2007
3	CholesterolIBA 03/2024 - 01/2019
3	Alanine Transaminase (SGPT)IBA 10/2023 - 03/2019
3	Air Pollutants (Pollutants, Air)IBA 01/2023 - 08/2017
3	AsbestosIBA 01/2023 - 01/2015
3	ArsenicIBA 01/2023 - 02/2006
3	AntigensIBA 01/2023 - 01/2014
3	Heavy MetalsIBA 10/2021 - 01/2015
3	Messenger RNA (mRNA)IBA 01/2021 - 05/2015
3	CadmiumIBA 01/2021 - 01/2016
3	SuspensionsIBA 05/2020 - 01/2011
3	Small Interfering RNA (siRNA)IBA 01/2019 - 05/2015
3	Tumor Biomarkers (Tumor Markers)IBA 01/2018 - 01/2014
3	CarcinogensIBA 11/2013 - 07/2006
2	Indicators and Reagents (Reagents)IBA 03/2024 - 01/2018
2	Polychlorinated Biphenyls (PCBs)IBA 03/2024 - 01/2023
2	HDL CholesterolIBA 03/2024 - 02/2019
2	LDL CholesterolIBA 03/2024 - 02/2019
2	6-methyladenineIBA 01/2024 - 12/2022
2	Antihypertensive Agents (Antihypertensives)IBA 11/2023 - 12/2017
2	Benzo(a)pyreneIBA 10/2023 - 04/2022
2	Alkaline PhosphataseIBA 10/2023 - 01/2023
2	DimethylformamideIBA 10/2023 - 07/2020
2	propylene oxideIBA 10/2023 - 01/2022
2	1,3-butadiene (divinyl)IBA 10/2023 - 01/2023
2	8-Hydroxy-2'-DeoxyguanosineIBA 07/2023 - 01/2019
2	OzoneIBA 07/2023 - 06/2023
2	Pyrethrins (Pyrethroids)FDA Link 07/2023 - 12/2022
2	Warfarin (Coumadin)FDA LinkGeneric 06/2023 - 01/2021
2	Interleukin-6 (Interleukin 6)IBA 04/2023 - 04/2012
2	Folic Acid (Vitamin M)FDA LinkGeneric 04/2023 - 01/2023
2	Long Noncoding RNAIBA 03/2023 - 08/2016
2	Carbon MonoxideIBA 01/2023 - 04/2016
2	AntioxidantsIBA 01/2023 - 01/2011

Therapy/Procedure

5	Therapeutics 09/2023 - 01/2020
3	Immunotherapy 01/2023 - 01/2020
2	Radiotherapy 10/2023 - 01/2023